Number needed to treat and reduction of outcomes with RAAS inhibitors

Number Needed to Treat

Number needed to treat (NNT); number needed to harm (NNH).

Number needed to treat and baseline risks.

Deriving number-needed-to-treat and number-needed-to-harm from the SAINT I trial results.

Deriving Number-Needed-to-Treat and Number-Needed-to-Harm From the Saint I Trial Results To the Editor: In their recent publication regarding interpretation of the Stroke-Acute Ischemic NXY Treatment (SAINT I) trial,1 Koziol and Feng use the definition, but not the derivation method, for number-needed-to-treat (NNT) and number-needed-to-harm (NNH) that was previously described.2 As a result the...

Reporting number needed to treat and absolute risk reduction in randomized controlled trials.

CONTEXT Ongoing efforts to improve the quality of reporting for randomized controlled trials (RCTs) include the Consolidated Standards of Reporting Trials (CONSORT) statement. We examined the frequency of explicit reporting of the number needed to treat (NNT) and the absolute risk reduction (ARR) in RCTs. METHODS Five frequently cited journals were investigated: Annals of Internal Medicine, B...